MailEnable 'MESMTRPC.exe' SMTP Service Multiple Remote Denial of Service Vulnerabilities

According to its banner, the remote MailEnable is prone to multiple remote denial-of-service vulnerabilities. An attacker can exploit these issue to crash the affected application, denying service to legitimate users. MailEnable 4.25 Standard Edition, Professional Edition, and Enterprise Edition are vulnerable other versions may also be affected.
The vendor has released hotfix ME-10044. Please see the references for more information.